Description
⚠ For laboratory research use only. Not for human consumption.
CAS NO: 86168-78-7
Molecular Formula: C149H246N44O42S
Molecular Weight: 3357.88 g/mol
Form: Lyophilized powder
Appearance: white powder
Storage: 2-8°
Purity: ≥99%
Sermorelin is a synthetic peptide that mimics Growth Hormone-Releasing Hormone (GHRH), the hormone your body naturally uses to signal the pituitary gland to release growth hormone (GH). Rather than supplying growth hormone directly, Sermorelin stimulates your body’s own GH production in a more natural, pulsatile pattern.
What researchers study Sermorelin for
- Growth hormone and IGF-1 production
- Body composition and fat metabolism
- Recovery and tissue repair
- Sleep quality
- Healthy aging
- Energy and exercise recovery
How it works
Sermorelin binds to GHRH receptors in the pituitary gland, triggering the release of growth hormone. Because it works through the body’s natural feedback systems, it generally produces GH pulses rather than the sustained elevations seen with direct HGH administration.
Sermorelin vs Tesamorelin
| Feature | Sermorelin | Tesamorelin |
| Type | GHRH analog (1-29) | Modified GHRH analog |
| Main purpose in research | General GH support | Stronger IGF-1 and visceral fat research |
| Clinical history | Used for GH deficiency evaluation/treatment | FDA-approved as Egrifta for HIV-associated lipodystrophy |
| GH stimulation | Moderate | Typically stronger and longer-lasting |
Researchers have observed associations with:
- Increased IGF-1 levels
- Improved lean body mass
- Reduced body fat
- Improved sleep quality
- Enhanced recovery and well-being in some populations
Research status
Sermorelin was previously FDA-approved for certain pediatric growth hormone deficiency indications, but commercial production was discontinued in 2008. It remains available in some settings through compounding pharmacies and continues to be studied in growth hormone-related research.
EXPERIMENTAL PREPARATION
For accurate research application:
- Reconstitutewith appropriate volume of bacteriostatic water
- Inject BAC water slowly down the inside wall of the vial, rather than directly onto the powder.
- Gently swirluntil fully dissolved (do not vortex)
- Administerimmediately or store at 4°C protected from light
- Reconstituted: Stable 30 days at 4°C
IMPORTANT: This product is intended strictly for laboratory research purposes only. NOT for human or animal consumption. NOT for medical or diagnostic use. These products have not undergone evaluation by the U.S. Food and Drug Administration. By purchasing, you confirm compliance with all applicable regulations.




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