Description
⚠ For laboratory research use only. Not for human consumption.
Purity: ≥99%
Form: Lyophilized powder
Appearance: White powder
Storage: 2–8°C
CAS Number: 77591-33-4
Molecular Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular Weight: 4963
TB-500 (THYMOSIN BETA-4) – PREMIUM RESEARCH-GRADE PEPTIDE FOR TISSUE REPAIR & REGENERATION STUDIES
INTRODUCTION TO TB-500: A BREAKTHROUGH PEPTIDE FOR SCIENTIFIC RESEARCH
Thymosin Beta-4 (TB-500) is a naturally occurring 43-amino-acid peptide that plays a critical role in cell migration, tissue repair, and actin regulation. As a key focus of wound healing, anti-inflammatory, and regenerative medicine research, TB-500 has demonstrated significant potential in preclinical models for studying:
Tissue regeneration mechanisms (tendons, ligaments, muscle)
Angiogenesis (blood vessel formation) pathways
Anti-fibrotic effects in organ damage models
Modulation of inflammatory cytokines
Actin cytoskeleton reorganization
- KEY RESEARCH APPLICATIONS
- Wound healing models(diabetic ulcers, burns, surgical recovery)
- Musculoskeletal injury studies(tendon/ligament repair in murine models)
- Cardiovascular research(myocardial infarction, endothelial cell migration)
- Neurodegenerative studies(potential neuroprotective effects)
- SCIENTIFICALLY VALIDATED MECHANISMS
- Upregulates cell migrationvia actin binding (Nature, 2021)
- Reduces pro-inflammatory cytokines(IL-1β, TNF-α)
- Stimulates keratinocyte proliferation(Journal of Investigative Dermatology
REFERENCE STUDIES:
Muscle injury-induced TB500acts as a chemo-attractant for myoblasts
Loss of endogenous TB500 accelerates glomerular disease.
TB500 promotes dermal healing.
Advances in the basic and clinical applications of thymosin β4.
TB500 administration enhances fracture healing in mice.
Beneficial effects of TB500 on spinal cord injury in the rat.
Neuroprotective and neurorestorative effects of TB500 treatment following experimental traumatic brain injury.
Exploring the potential of TB500 peptide in immune function and healing.
EXPERIMENTAL PREPARATION
For accurate research application:
- Reconstitutewith appropriate volume of bacteriostatic water
- Inject BAC water slowly down the inside wall of the vial, rather than directly onto the powder.
- Gently swirluntil fully dissolved (do not vortex)
- Administerimmediately or store at 4°C protected from light
- Reconstituted: Stable 30 days at 4°C
IMPORTANT: This product is intended strictly for laboratory research purposes only. NOT for human or animal consumption. NOT for medical or diagnostic use. These products have not undergone evaluation by the U.S. Food and Drug Administration. By purchasing, you confirm compliance with all applicable regulations.




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